Haughey, Anne-Marie and Guilhabert, Benoit and Kanibolotsky, Alexander L and Skabara, Peter J and Dawson, Martin D and Burley, Glenn A and Laurand, Nicolas (2014) An oligofluorene truxene based distributed feedback laser for biosensing
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چکیده
The first example of an all-organic oligofluorene truxene based distributed feedback laser for the detection of a specific protein–small molecule interaction is reported. The protein avidin was detected down to 1 μg mL 1 using our biotin-labelled biosensor platform. This interaction was both selective and reversible when biotin was replaced with desthiobiotin. Avidin detection was not perturbed by Bovine Serum Albumin up to 50;000 μg mL 1 . Our biosensor offers a new detection platform that is both highly sensitive, modular and potentially re-usable. & 2013 The Authors. Published by Elsevier B.V. All rights reserved.
منابع مشابه
An oligofluorene truxene based distributed feedback laser for biosensing applications.
The first example of an all-organic oligofluorene truxene based distributed feedback laser for the detection of a specific protein-small molecule interaction is reported. The protein avidin was detected down to 1 μg mL(-1) using our biotin-labelled biosensor platform. This interaction was both selective and reversible when biotin was replaced with desthiobiotin. Avidin detection was not perturb...
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تاریخ انتشار 2018